Structure of PDB 3ice Chain B Binding Site BS03

Receptor Information

>3ice Chain B (length=408) Species: 83333 (Escherichia coli K-12)

MNLTELKNTPVSELITLGENMGRKQDIIFAILKQHAKSGEDIFGDGVLEI
LQDGFGFLRSADSSYLAGPDDIYVSPSQIRRFNLRTGDTISGKIRPPKEG
ERYFALLKVNEVNFDKPENARNKILFENLTPLHANSRLRMERGNGSTEDL
TARVLDLASPIGRGQRGLIVAPPKAGKTMLLQNIAQSIAYNHPDCVLMVL
LIDERPEEVTEMQRLVKGEVVASTFDEPASRHVQVAEMVIEKAKRLVEHK
KDVIILLDSITRLARAYNTVVPASGKVLTGGVDANALHRPKRFFGAARNV
EEGGSLTIIATALIDTGSKMDEVIYEEFKGTGNMELHLSRKIAEKRVFPA
IDYNRSGTRKEELLTTQEELQKMWILRKIIHPMGEIDAMEFLINKLAMTK
TNDDFFEM

Ligand information

• Ligand ID: BEF
• InChI: InChI=1S/Be.3FH/h;3*1H/q+2;;;/p-3
• InChIKey: OGIAHMCCNXDTIE-UHFFFAOYSA-K
• SMILES:
  OpenEye OEToolkits 1.5.0: [Be-](F)(F)F
  ACDLabs 10.04
  CACTVS 3.341: F[Be-](F)F
• Formula: Be F3
• Name: BERYLLIUM TRIFLUORIDE ION
• PDB chain: 3ice Chain A Residue 1002

Receptor-Ligand Complex Structure

Structure summary

• PDB: 3ice Running in reverse: the structural basis for translocation polarity in hexameric helicases.
• Resolution: 2.8 Å
• Binding residue (original residue number in PDB): G337 R366
• Binding residue (residue number reindexed from 1): G330 R359
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 3.6.4.-

Gene Ontology

Molecular Function

• GO:0003676 nucleic acid binding
• GO:0003723 RNA binding
• GO:0004386 helicase activity
• GO:0005515 protein binding
• GO:0005524 ATP binding
• GO:0008186 ATP-dependent activity, acting on RNA
• GO:0016787 hydrolase activity
• GO:0016887 ATP hydrolysis activity
• GO:0042802 identical protein binding

Biological Process

• GO:0006353 DNA-templated transcription termination

Cellular Component

• GO:0005829 cytosol
• GO:0016020 membrane

External links

• PDB: RCSB:3ice, PDBe:3ice, PDBj:3ice
• PDBsum: 3ice
• PubMed: 19879839
• UniProt: P0AG30|RHO_ECOLI Transcription termination factor Rho (Gene Name=rho)