Structure of PDB 3epk Chain B Binding Site BS03

Receptor Information
>3epk Chain B (length=402) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SKKVIVIAGTTGVGKSQLSIQLAQKFNGEVINSDSMQVYKDIPIITNKHP
LQEREGIPHHVMNHVDWSEEYYSHRFETECMNAIEDIHRRGKIPIVVGGT
HYYLQTLFNKRVDTKSSERKLTRKQLDILESTDPDVIYNTLVKCDPDIAT
KYHPNDYRRVQRMLEIYYKTGKKPSETFNEQKITLKFDTLFLWLYSKPEP
LFQRLDDRVDDMLERGALQEIKQLYEYYSQNKFTPEQCENGVWQVIGFKE
FLPWLTVKLEDCIERMKTRTRQYAKRQVKWIKKMLIPDIKGDIYLLDATD
LSQWDTNASQRAIAISNDFISNRPIKQERAPKALEELLSKGETTMKKLDD
WTHYTCNVCRNADGKNVVAIGEKYWKIHLGSRRHKSNLKRNTRQADFEKW
KI
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain3epk Chain B Residue 422 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3epk Crystallographic snapshots of eukaryotic dimethylallyltransferase acting on tRNA: insight into tRNA recognition and reaction mechanism.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		D78 W79
Binding residue
(residue number reindexed from 1)		D66 W67
Annotation score1
Enzymatic activity
Enzyme Commision number 2.5.1.75: tRNA dimethylallyltransferase.
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0005524 ATP binding
GO:0008270 zinc ion binding
GO:0016740 transferase activity
GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups
GO:0046872 metal ion binding
GO:0052381 tRNA dimethylallyltransferase activity
Biological Process
GO:0006400 tRNA modification
GO:0008033 tRNA processing
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3epk, PDBe:3epk, PDBj:3epk
PDBsum3epk
PubMed18852462
UniProtP07884|MOD5_YEAST tRNA dimethylallyltransferase (Gene Name=MOD5)

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