Structure of PDB 2wwy Chain B Binding Site BS03

Receptor Information
>2wwy Chain B (length=530) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLVM
PTGGGKSLCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNA
SSSKEHVKWVHAEMVNKNSELKLIYVTPEKIAKSKMFMSRLEKAYEARRF
TRIAVDEVHCCSQWGHDFRPDYKALGILKRQFPNASLIGLTATATNHVLT
DAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDFIEDIVKLINGRYK
GQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKWSAN
EIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKAD
CILYYGFGDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLMAQHFD
EVWNSEACNKMCDNCCKDSAFERKNITEYCRDLIKILKQAEELNEKLTPL
KLIDSWMGKGAAKLRVAGVVAPTLPREDLEKIIAHFLIQQYLKEDYSFTA
YATISYLKIGPKANLLNNEAHAITMQVTKS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2wwy Recq1 Helicase-Driven DNA Unwinding, Annealing, and Branch Migration: Insights from DNA Complex Structures
Resolution2.9 Å
Binding residue
(original residue number in PDB)		D230 R232 Q324 A346 M429 Y564
Binding residue
(residue number reindexed from 1)		D167 R169 Q261 A283 M366 Y501
Enzymatic activity
Enzyme Commision number 5.6.2.4: DNA 3'-5' helicase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0004386 helicase activity
GO:0005524 ATP binding
Biological Process
GO:0006310 DNA recombination

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Molecular Function
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Biological Process
External links
PDB RCSB:2wwy, PDBe:2wwy, PDBj:2wwy
PDBsum2wwy
PubMed25831490
UniProtP46063|RECQ1_HUMAN ATP-dependent DNA helicase Q1 (Gene Name=RECQL)

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