Structure of PDB 2qts Chain B Binding Site BS03

Receptor Information
>2qts Chain B (length=420) Species: 9031 (Gallus gallus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LKRVVWALCFMGSLALLALVCTNRIQYYFLYPHVTKLDEVAATRLTFPAV
TFCNLNEFRFSRVTKNDLYHAGELLALLNNRYEIPDTQTADEKQLEILQD
KANFRNFKPKPFNMLEFYDRAGHDIREMLLSCFFRGEQCSPEDFKVVFTR
YGKCYTFNAGQDGKPRLITMKGGTGNGLEIMLDIQQDEYLPVWGETDETS
FEAGIKVQIHSQDEPPLIDQLGFGVAPGFQTFVSCQEQRLIYLPPPWGDC
KATTGDSEFYDTYSITACRIDCETRYLVENCNCRMVHMPGDAPYCTPEQY
KECADPALDFLVEKDNEYCVCEMPCNVTRYGKELSMVKIPSKASAKYLAK
KYNKSEQYIGENILVLDIFFEALNYETIEQKKAYEVAGLLGDIGGQMGLF
IGASILTVLELFDYAYEVIK
Ligand information
Ligand IDGLC
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1
InChIKeyWQZGKKKJIJFFOK-DVKNGEFBSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(C1C(C(C(C(O1)O)O)O)O)O
OpenEye OEToolkits 1.5.0C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O)O)O)O)O
CACTVS 3.341OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
CACTVS 3.341OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O
ACDLabs 10.04OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namealpha-D-glucopyranose;
alpha-D-glucose;
D-glucose;
glucose
ChEMBLCHEMBL423707
DrugBank
ZINCZINC000003861213
PDB chain2qts Chain H Residue 2 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2qts Structure of acid-sensing ion channel 1 at 1.9A resolution and low pH
Resolution1.9 Å
Binding residue
(original residue number in PDB)		R65 Y68
Binding residue
(residue number reindexed from 1)		R24 Y27
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005272 sodium channel activity
GO:0015280 ligand-gated sodium channel activity
Biological Process
GO:0006814 sodium ion transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2qts, PDBe:2qts, PDBj:2qts
PDBsum2qts
PubMed17882215
UniProtQ1XA76|ASIC1_CHICK Acid-sensing ion channel 1 (Gene Name=ASIC1)

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