Structure of PDB 2pfj Chain B Binding Site BS03

Receptor Information

>2pfj Chain B (length=130) Species: 10760 (Escherichia phage T7) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

RSGLEDKVSKQLESKGIKFEYEEWKVPYVIPASNHTYTPDFLLPNGIFVE
TAGLWESDDRKKHLLIREQHPELDIRIVFSSSRTKLYKGSPTSYGEFCEK
HGIKFADKLIPAEWIKEPKKEVPFDRLKRK

Ligand information

InChI=1S/Ca/q+2

BHPQYMZQTOCNFJ-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Ca++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Ca+2]

Formula

Ca

Name

CALCIUM ION

PDB chain

2pfj Chain B Residue 150 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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PDB	2pfj The structural basis of Holliday junction resolution by T7 endonuclease I.
Resolution	3.1 Å
Binding residue (original residue number in PDB)	D55 E65 T66
Binding residue (residue number reindexed from 1)	D40 E50 T51
Annotation score	4

Enzymatic activity

Enzyme Commision number

3.1.21.2: deoxyribonuclease IV.

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0004519	endonuclease activity
GO:0008821	crossover junction DNA endonuclease activity
GO:0008833	deoxyribonuclease IV (phage-T4-induced) activity
GO:1990238	double-stranded DNA endonuclease activity

	Biological Process
GO:0015074	DNA integration
GO:0016032	viral process
GO:0039657	symbiont-mediated suppression of host gene expression
GO:0099015	degradation of host chromosome by virus

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Molecular Function

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Biological Process

External links

PDB	RCSB:2pfj, PDBe:2pfj, PDBj:2pfj
PDBsum	2pfj
PubMed	17873858
UniProt	P00641\|ENDO_BPT7 Endonuclease I (Gene Name=3)

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