Structure of PDB 2han Chain B Binding Site BS03

Receptor Information
>2han Chain B (length=87) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RVQEELCLVCGDRASGYHYNALTCEGCKGFFRRSVTKSAVYCCKFGRACE
MDMYMRRKCQECRLKKCLAVGMRPECVVPENQCAMKR
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2han Chain B Residue 353 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2han Novel DNA-binding element within the C-terminal extension of the nuclear receptor DNA-binding domain.
Resolution1.95 Å
Binding residue
(original residue number in PDB)		C7 C10 C24 C27
Binding residue
(residue number reindexed from 1)		C7 C10 C24 C27
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:2han, PDBe:2han, PDBj:2han
PDBsum2han
PubMed17426125
UniProtP34021|ECR_DROME Ecdysone receptor (Gene Name=EcR)

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