Structure of PDB 2g77 Chain B Binding Site BS03

Receptor Information
>2g77 Chain B (length=173) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RSRIFKIIVIGDSNVGKTCLTYRFCAGRFPDRTEATIGVDFRERAVDIDG
ERIKIQLWDTAGQERFRKSMVQHYYRNVHAVVFVYDMTNMASFHSLPAWI
EECKQHLLANDIPRILVGNKCDLRSAIQVPTDLAQKFADTHSMPLFETSA
KNPNDNDHVEAIFMTLAHKLKSH
Ligand information
Ligand IDAF3
InChIInChI=1S/Al.3FH/h;3*1H/q+3;;;/p-3
InChIKeyKLZUFWVZNOTSEM-UHFFFAOYSA-K
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		F[Al](F)F
FormulaAl F3
NameALUMINUM FLUORIDE
ChEMBL
DrugBank
ZINC
PDB chain2g77 Chain B Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2g77 TBC-domain GAPs for Rab GTPases accelerate GTP hydrolysis by a dual-finger mechanism.
Resolution2.26 Å
Binding residue
(original residue number in PDB)		S42 K46 T65 A90 G91
Binding residue
(residue number reindexed from 1)		S13 K17 T36 A61 G62
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0032482 Rab protein signal transduction

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Molecular Function
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Biological Process
External links
PDB RCSB:2g77, PDBe:2g77, PDBj:2g77
PDBsum2g77
PubMed16855591
UniProtO35963|RB33B_MOUSE Ras-related protein Rab-33B (Gene Name=Rab33b)

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