Structure of PDB 2fkc Chain B Binding Site BS03

Receptor Information
>2fkc Chain B (length=247) Species: 727 (Haemophilus influenzae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNLVELGSKTAKDGFKNEKDIADRFENWKENSEAQDWLVTMGHNLDEIKS
VKAVVLSGYKSDINVQVLVFYKDALDIHNIQVKLVSNKRGFNQIDKHWLA
HYQEMWKFDDNLLRILRHFTGELPPYHSNTKDKRRMFMTEFSQEEQNIVL
NWLEKNRVLVLTDILRGRGDFAAEWVLVAQKVSNNARWILRNINEVLQHY
GSGDISLSPRGSINFGRVTIQRKGGDNGRETANMLQFKIDPTELFDI
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain2fkc Chain B Residue 248 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2fkc DNA nicking by HinP1I endonuclease: bending, base flipping and minor groove expansion.
Resolution2.39 Å
Binding residue
(original residue number in PDB)		D62 Q81 V82
Binding residue
(residue number reindexed from 1)		D62 Q81 V82
Annotation score4
Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:2fkc, PDBe:2fkc, PDBj:2fkc
PDBsum2fkc
PubMed16473850
UniProtQ5I6E6

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