Structure of PDB 1z1b Chain B Binding Site BS03

Receptor Information
>1z1b Chain B (length=350) Species: 10710 (Lambdavirus lambda) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HERRDLPPNLYIRNNGYYCYRDPRTGKEFGLGRDRRIAITEAIQANIELF
SGHKHKPLTARINSDNSVTLHSWLDRYEKILASRGIKQKTLINYMSKIKA
IRRGLPDAPLEDITTKEIAAMLNGYIDEGKAASAKLIRSTLSDAFREAIA
EGHITTNHVAATRAAKSKVRRSRLTADEYLKIYQAAESSPCWLRLAMELA
VVTGQRVGDLCEMKWSDIVDGYLYVEQSKTGVKIAIPTALHIDALGISMK
ETLDKCKEILGGETIIASTRREPLSSGTVSRYFMRARKASGLSFEGDPPT
FHELRSLSARLYEKQISDKFAQHLLGHKSDTMASQYRDDRGREWDKIEIK
Ligand information
Receptor-Ligand Complex Structure
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PDB1z1b A structural basis for allosteric control of DNA recombination by lambda integrase.
Resolution3.8 Å
Binding residue
(original residue number in PDB)		Y23 K33 E34 F35 G36
Binding residue
(residue number reindexed from 1)		Y17 K27 E28 F29 G30
Enzymatic activity
Enzyme Commision number 2.7.7.-
3.1.-.-
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0008907 integrase activity
GO:0016740 transferase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006310 DNA recombination
GO:0015074 DNA integration
GO:0032359 provirus excision
GO:0044826 viral genome integration into host DNA
GO:0046718 symbiont entry into host cell
GO:0075713 establishment of integrated proviral latency

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Molecular Function
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Biological Process
External links
PDB RCSB:1z1b, PDBe:1z1b, PDBj:1z1b
PDBsum1z1b
PubMed15973401
UniProtP03700|VINT_LAMBD Integrase (Gene Name=int)

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