Structure of PDB 1ytu Chain B Binding Site BS03

Receptor Information
>1ytu Chain B (length=427) Species: 224325 (Archaeoglobus fulgidus DSM 4304) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MMEYKIVENGLTYRIGNGASVPISNTGELIKGLRNYGPYEVPSLKYNQIA
LIHNNQFSSLINQLKSQISSKIDEVWHIHNINISEFIYDSPHFDSIKSQV
DNAIDTGVDGIMLVLPEYNTPLYYKLKSYLINSIPSQFMRYDILSNRNLT
FYVDNLLVQFVSKLGGKPWILNVDPEKGSDIIIGTGATRIDNVNLFCFAM
VFKKDGTMLWNEISPIVTSSEYLTYLKSTIKKVVYGFKKSNPDWDVEKLT
LHVSGKRPKMKDGETKILKETVEELKKQEMVSRDVKYAILHLNETHPFWV
MGDPNNRFHPYEGTKVKLSSKRYLLTLLQPYLKRNGLEMVTPIKPLSVEI
VSDNWTSEEYYHNVHEILDEIYYLSKMNWRGFRSRNLPVTVNYPKLVAGI
IANVNRYGGYPINPEGNRSLQTNPWFL
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain1ytu Chain B Residue 428 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1ytu Structural basis for 5'-end-specific recognition of guide RNA by the A. fulgidus Piwi protein.
Resolution2.5 Å
Binding residue
(original residue number in PDB)
Q159 L427
Binding residue
(residue number reindexed from 1)
Q159 L427
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:1ytu, PDBe:1ytu, PDBj:1ytu
PDBsum1ytu
PubMed15800629
UniProtO28951|PIWI_ARCFU Piwi protein (Gene Name=AF_1318)

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