Structure of PDB 1kqf Chain B Binding Site BS03

Receptor Information
>1kqf Chain B (length=289) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AMETQDIIKRSATNSITPPSQVRDYKAEVAKLIDVSTCIGCKACQVACSE
WNDIRDEVGHCVGVYDNPADLSAKSWTVMRFSETEQNGKLEWLIRKDGCM
HCEDPGCLKACPSAGAIIQYANGIVDFQSENCIGCGYCIAGCPFNIPRLN
KEDNRVYKCTLCVDRVSVGQEPACVKTCPTGAIHFGTKKEMLELAEQRVA
KLKARGYEHAGVYNPEGVGGTHVMYVLHHADQPELYHGLPKDPKIDTSVS
LWKGALKPLAAAGFIATFAGLIFHYIGIGPNKEVDDDEE
Ligand information
Ligand IDSF4
InChIInChI=1S/4Fe.4S
InChIKeyLJBDFODJNLIPKO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7[S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
CACTVS 3.385S1[Fe]S[Fe]1.S2[Fe]S[Fe]2
FormulaFe4 S4
NameIRON/SULFUR CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain1kqf Chain B Residue 807 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1kqf Molecular basis of proton motive force generation: structure of formate dehydrogenase-N.
Resolution1.6 Å
Binding residue
(original residue number in PDB)		C100 M101 H102 C103 P106 C108 V126 C143 I147 P148 K159
Binding residue
(residue number reindexed from 1)		C99 M100 H101 C102 P105 C107 V125 C142 I146 P147 K158
Annotation score1
Enzymatic activity
Enzyme Commision number 1.2.1.2: Transferred entry: 1.17.1.9.
Gene Ontology
Molecular Function
GO:0009055 electron transfer activity
GO:0036397 formate dehydrogenase (quinone) activity
GO:0046872 metal ion binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0006788 heme oxidation
GO:0009061 anaerobic respiration
GO:0015944 formate oxidation
GO:0019645 anaerobic electron transport chain
GO:0045333 cellular respiration
Cellular Component
GO:0005886 plasma membrane
GO:0009326 formate dehydrogenase complex
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1kqf, PDBe:1kqf, PDBj:1kqf
PDBsum1kqf
PubMed11884747
UniProtP0AAJ3|FDNH_ECOLI Formate dehydrogenase, nitrate-inducible, iron-sulfur subunit (Gene Name=fdnH)

[Back to BioLiP]