Structure of PDB 1iaw Chain B Binding Site BS03

Receptor Information
>1iaw Chain B (length=304) Species: 68170 (Lentzea aerocolonigenes) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EPDDDLERVRATLYSLDPDGDRTAGVLRDTLDQLYDGQRTGRWNFDQLHK
TEKTHMGTLVEINLHREFQFGDGFETDYEIAGVQVDCKFSMSQGAWMLPP
ESIGHICLVIWASDQQCAWTAGLVKVIPQFLGTANRDLKRRLTPEGRAQV
VKLWPDHGKLQENLLLHIPGDVRDQIFSAKSSRGNQHGQARVNELFRRVH
GRLIGRAVIATVAQQDDFMKRVRGSGGARSILRPEGIIILGHQDNDPKVA
NDLGLPVPRKGQVVAARVVPADEGDQRQTAEIQGRRWAVAVPGDPIVEAP
VVPR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1iaw Structure of NaeI-DNA complex reveals dual-mode DNA recognition and complete dimer rearrangement.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		K59 K62 T63 D86 K97 F98 S99 M100 M106 E110 D146 K148 R150
Binding residue
(residue number reindexed from 1)		K50 K53 T54 D77 K88 F89 S90 M91 M97 E101 D137 K139 R141
Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0009036 type II site-specific deoxyribonuclease activity
Biological Process
GO:0009307 DNA restriction-modification system

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1iaw, PDBe:1iaw, PDBj:1iaw
PDBsum1iaw
PubMed11473254
UniProtP50187|T2N1_LENAE Type II restriction enzyme NaeI (Gene Name=naeIR)

[Back to BioLiP]