Structure of PDB 1gqt Chain B Binding Site BS03

Receptor Information
>1gqt Chain B (length=307) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QNAGSLVVLGSINADHILNLQSFPTPGETVTGNHYQVAFGGKGANQAVAA
GRSGANIAFIACTGDDSIGESVRQQLATDNIDITPVSVIKGESTGVALIF
VNGEGENVIGIHAGANAALSPALVEAQRERIANASALLMQLESPLESVMA
AAKIAHQNKTIVALNPAPARELPDELLALVDIITPNETEAEKLTGIRVEN
DEDAAKAAQVLHEKGIRTVLITLGSRGVWASVNGEGQRVPGFRVQAVDTI
AAGDTFNGALITALLEEKPLPEAIRFAHAAAAIAVTRKGAQPSVPWREEI
DAFLDRQ
Ligand information
Ligand IDRIB
InChIInChI=1S/C5H10O5/c6-1-2-3(7)4(8)5(9)10-2/h2-9H,1H2/t2-,3-,4-,5+/m1/s1
InChIKeyHMFHBZSHGGEWLO-AIHAYLRMSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(C1C(C(C(O1)O)O)O)O
CACTVS 3.341OC[CH]1O[CH](O)[CH](O)[CH]1O
CACTVS 3.341OC[C@H]1O[C@H](O)[C@H](O)[C@@H]1O
OpenEye OEToolkits 1.5.0C([C@@H]1[C@H]([C@H]([C@H](O1)O)O)O)O
ACDLabs 10.04OC1C(OC(O)C1O)CO
FormulaC5 H10 O5
Namealpha-D-ribofuranose;
alpha-D-ribose;
D-ribose;
ribose
ChEMBLCHEMBL606078
DrugBank
ZINCZINC000003860714
PDB chain1gqt Chain B Residue 1311 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1gqt Activation of Ribokinase by Monovalent Cations.
Resolution2.34 Å
Binding residue
(original residue number in PDB)		N14 D16 G42 N46 E143 D255
Binding residue
(residue number reindexed from 1)		N13 D15 G41 N45 E142 D254
Annotation score5
Enzymatic activity
Catalytic site (original residue number in PDB) A252 A253 G254 D255
Catalytic site (residue number reindexed from 1) A251 A252 G253 D254
Enzyme Commision number 2.7.1.15: ribokinase.
Gene Ontology
Molecular Function
GO:0004747 ribokinase activity
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
Biological Process
GO:0006014 D-ribose metabolic process
GO:0016310 phosphorylation
GO:0019303 D-ribose catabolic process
GO:0046835 carbohydrate phosphorylation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1gqt, PDBe:1gqt, PDBj:1gqt
PDBsum1gqt
PubMed11786021
UniProtP0A9J6|RBSK_ECOLI Ribokinase (Gene Name=rbsK)

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