Structure of PDB 8oin Chain Aa Binding Site BS03

Receptor Information
>8oin Chain Aa (length=381) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DTKMLWKHKALQKYMENLSKEYQTLEQCLQHIPVNEENRRSLNRRHAELA
PLAAIYQEIQETEQAIEELESMCKSLNKQDEKQLQELALEERQTIDQKIN
MLYNELFQSLVPKEKYDKNDVILEVTAGRTTGGDICQQFTREIFDMYQNY
SCYKHWQFELLNYTPADYGGLHHAAARISGDGVYKHLKYEGGIHRVQRIP
EVGLSSRMQRIHTGTMSVIVLPQPDEVDVKLDPKDLRIDTFRAKGAGGQH
VNKTDSAVRLVHIPTGLVVECQQERSQIKNKEIAFRVLRARLYQQIIEKD
KRQQQSARKLQVGTRAQSERIRTYNFTQDRVSDHRIAYEVRDIKEFLCGG
KGLDQLIQRLLQSADEEAIAELLDEHLKSAK
Ligand information
>8oin Chain AG (length=71) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aguaaggucagcuaaauaagcuaucgggcccauaccccgaaaauguuggu
uauacccuucccguacuacca
<<<<.<<..<<<<.....>>>>.<<<<<.......>>>>>.......<<.
.....>>...>>.>>>>....
Receptor-Ligand Complex Structure
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PDB8oin Molecular basis of translation termination at noncanonical stop codons in human mitochondria.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		G311 G312 Q313 R339 K343
Binding residue
(residue number reindexed from 1)		G247 G248 Q249 R275 K279
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003747 translation release factor activity
GO:0016149 translation release factor activity, codon specific
Biological Process
GO:0006412 translation
GO:0006415 translational termination
GO:0070126 mitochondrial translational termination
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8oin, PDBe:8oin, PDBj:8oin
PDBsum8oin
PubMed37141370
UniProtO75570|RF1M_HUMAN Peptide chain release factor 1, mitochondrial (Gene Name=MTRF1)

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