Structure of PDB 4v5j Chain AY Binding Site BS03

Receptor Information
>4v5j Chain AY (length=351) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LAQRLEGLRGYLDIPQKETRLKELERRLEDPSLWNDPEAARKVSQEAARL
RRTVDTFRSLESDLQGLLELMEELPAEEREALKPELEEAAKKLDELYHQT
LLNFPHAEKNAILTIQPGAGGTEACDWAEMLLRMYTRFAERQGFQVEVVD
LTPGPEAGIDYAQILVKGENAYGLLSPEAGVHRLVRPSPFDASGRRHTSF
AGVEVIPEVDEEVEVVLKPEELRIDVMRASGPGGQGVNTTDSAVRVVHLP
TGITVTCQTTRSQIKNKELALKILKARLYELERKKREEELKALRGEVRPI
EWGSQIRSYVLDKNYVKDHRTGLMRHDPENVLDGDLMDLIWAGLEWKAGR
R
Ligand information
Receptor-Ligand Complex Structure
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PDB4v5j Structure of the 70S ribosome bound to release factor 2 and a substrate analog provides insights into catalysis of peptide release.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		G125 T127 E128 S193 R200 R201 H202 T203
Binding residue
(residue number reindexed from 1)		G120 T122 E123 S188 R195 R196 H197 T198
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003747 translation release factor activity
GO:0016149 translation release factor activity, codon specific
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
GO:0006415 translational termination
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4v5j, PDBe:4v5j, PDBj:4v5j
PDBsum4v5j
PubMed20421507
UniProtQ5SM01|RF2_THET8 Peptide chain release factor RF2 (Gene Name=prfB)

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