Structure of PDB 7pzy Chain AP Binding Site BS03

Receptor Information
>7pzy Chain AP (length=103) Species: 237561 (Candida albicans SC5314) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VNVPKTRKTYCKGKECRKHTQHKVTQYKAGKASLFAQGKRRYDRKQSGYG
GQTKQIFHKKAKTTKKVVLRLECVVCKTKAQLPLKRCKHFELGGDKKQKG
QAL
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7pzy Chain AP Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7pzy E-site drug specificity of the human pathogen Candida albicans ribosome.
Resolution2.32 Å
Binding residue
(original residue number in PDB)
C12 C17 C74 C77
Binding residue
(residue number reindexed from 1)
C11 C16 C73 C76
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7pzy, PDBe:7pzy, PDBj:7pzy
PDBsum7pzy
PubMed35613268
UniProtA0A1D8PEV4|RL44_CANAL Large ribosomal subunit protein eL42 (Gene Name=RPL44)

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