Structure of PDB 8hl2 Chain AEFG Binding Site BS03

Receptor Information
>8hl2 Chain AEFG (length=725) Species: 330779 (Sulfolobus acidocaldarius DSM 639) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VEQVLSLMKDVTRVRNIGIIAHVDHGKTTTSDTLLAASGIISQEALALDY
LSVEQQRGITVKAANISLYHEIDGKGYVINLIDTPGHVDFSGRVTRSLRV
LDGSIVVIDAVEGIMTQTETVLRQSLEERVRPILFINKVDRLIKELKLSS
QEIQKRLIDLIIEVNNLIETYGEPEFKDQWKIKPELGNVVFGSAKDKWGF
SVPMAGKRGVKFSDVVNAYTSGDKAKIEELASKVPIHEALLDAVIKFVPN
PRDSQKYRIPKIWKGDLDSEIAKAMINADPNGPIVMMINDMKVDPHAGLV
ATGRVFSGTLRAGEEVWLVNAKRQQRILQVSLYMGAIRELAEEIPVGNIA
AALGMDAARSGETGVDIRFKDSVLGSFEKLHYISEPVVTISVEPRNPKDL
TKMIDALRKLSIEDSNLVVKINEETGEYLLSGMGFLHLEVSLQLLKENYG
LDVVTTPPIVVYRESIRNKSQVFEGKSPNKHNKLYISVEPLNNQTIDLIA
NGTIKEDMDNKEMAKILRDQAEWDYDEAKKIVAIDENINVFIDATSGVQH
LREIMDTLLQGFRLAMKEGPLAFEPVRGVKVVLHDAVVHEDPAHRGPAQL
YPAVRNAIFAGILTSKPTLLEPLQKLDIRIPMEYLGNVTAVITRKRGKVI
NVVQTGNVARVYAEIPVGESFELASELRASSAGRAFWGTEFSRWAPVPDS
ILVDLIMKIRERKGKPKQLPKVEDF
Ligand information
>8hl2 Chain APTN (length=76) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcccggauagcucagucgguagagcaggggauugaaaauccccguguccu
ugguucgauuccgaguccgggcacca
<<<<<<...<<<<........>>>><<<<<<<.....>>>>>>.>...<<
<<<.......>>>>>.>>>>>>....
Receptor-Ligand Complex Structure
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PDB8hl2 Cryo-EM Structures and Translocation Mechanism of Crenarchaeota Ribosome
Resolution4.1 Å
Binding residue
(original residue number in PDB)		K490 H491 H604
Binding residue
(residue number reindexed from 1)		K480 H481 H594
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003746 translation elongation factor activity
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0006412 translation
GO:0006414 translational elongation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8hl2, PDBe:8hl2, PDBj:8hl2
PDBsum8hl2
PubMed37604686
UniProtP23112|EF2_SULAC Elongation factor 2 (Gene Name=fusA)

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