Structure of PDB 8b6f Chain AB Binding Site BS03

Receptor Information
>8b6f Chain AB (length=688) Species: 312017 (Tetrahymena thermophila SB210) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KQIEIFIDGKPAKVDDSYTIFQACYENGVIVPRFCYHERLSVAGNCRMCL
VEVENVPKPVAACASQVVPGMKIKTKSEKTRIHRGNVMEFLLANHPLDCP
ICDQGGECDLQDISSVYGYGISRYNEYKRAVEDKNYGPLVATSMNRCIHC
TRCVRFATQIAGVEDLGKTGRGKAAEIGTYVEKTFNTELSGNVVDVCPVG
ALTNAPYAFTSRPWELKSFYTSDVFDTLGSAIQVDTRGPEIMRVLPRIHE
EINEEWISDKTRHAFDGLKRQRINSPMKRSKDGNYEDIFWEEAIQTISKK
CLNTPSDQIGAIIGEFADIESITALKDFLNRLDVDNFEVRQHGNLKVSPD
FRANYLMNSKITGVEDADVLLLVGCNPRYEAPVLNARILKSTRKNLKVFN
IGTNQDLNYKNVHLGNSTKVLKEIADGTHPFAERLKKAKLPMIMVGASAL
EREDGAELYNTLKVISNKTGVISEEKSWNGFNILHKEMGRINALELGINP
TSVNKNAKLVFILGADNNLRPEDIPADAFVVYFGTHGDEGAYYADIILPT
AAYTEKNATWVNTEGRVQQGRLVVMPPGDAREDWQIIRALSEEAGVPLPY
DSLEELRYRVAELAPHLLKYDYIEPTIFGKVALSAQQGVKTTLSPTPITD
YIDNFYMTDAISRASVTMAKCSTAFNHEKFSNFKNLAK
Ligand information
Ligand IDSF4
InChIInChI=1S/4Fe.4S
InChIKeyLJBDFODJNLIPKO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7[S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
CACTVS 3.385S1[Fe]S[Fe]1.S2[Fe]S[Fe]2
FormulaFe4 S4
NameIRON/SULFUR CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain8b6f Chain AB Residue 803 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8b6f Structural basis of mitochondrial membrane bending by the I-II-III 2 -IV 2 supercomplex.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		H125 D128 C129 C132 C138 Q141 R176 V229
Binding residue
(residue number reindexed from 1)		H95 D98 C99 C102 C108 Q111 R146 V199
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003954 NADH dehydrogenase activity
GO:0008137 NADH dehydrogenase (ubiquinone) activity
GO:0016491 oxidoreductase activity
GO:0016651 oxidoreductase activity, acting on NAD(P)H
GO:0046872 metal ion binding
GO:0051536 iron-sulfur cluster binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0042773 ATP synthesis coupled electron transport
GO:0045333 cellular respiration
GO:1902600 proton transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8b6f, PDBe:8b6f, PDBj:8b6f
PDBsum8b6f
PubMed36949187
UniProtQ23KA9

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