Structure of PDB 5m1j Chain A6 Binding Site BS03

Receptor Information
>5m1j Chain A6 (length=539) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DMPDFHDEGEFDDYLNDDEYDLMNEVFPTLKAQLQDYQGWDNLSLKLALF
DNNFDLESTLAELKKTVQRYYKTTVPTKPKKPHDISAFVKSALPHLSFVV
LGHVDAGKSTLMGRLLYDLNIVNQSQLRKLQRESETMGKSSFKFAWIMDQ
TNEERERGVTVSICTSHFSTHRANFTIVDAPGHRDFVPNAIMGISQADMA
ILCVDCSTNAFESGFDLDGQTKEHMLLASSLGIHNLIIAMNKMDNVDWSQ
QRFEEIKSKLLPYLVDIGFFEDNINWVPISGFSGEGVYKIEYTDEVRQWY
NGPNLMSTLENAAFKISKENEGINKDDPFLFSVLEIIPSKKTSNDLALVS
GKLESGSIQPGESLTIYPSEQSCIVDKIQVGSQQGQSTNHEETDVAIKGD
FVTLKLRKAYPEDIQNGDLAASVDYSSIHSAQCFVLELTTFDMNRPLLPG
TPFILFIGVKEQPARIKRLISFIDKGNTASKKKIRHLGSKQRAFVEIELI
EVKRWIPLLTAHENDRLGRVVLRKDGRTIAAGKISEITQ
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain5m1j Chain A6 Residue 703 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5m1j Structural insights into ribosomal rescue by Dom34 and Hbs1 at near-atomic resolution.
Resolution3.3 Å
Binding residue
(original residue number in PDB)		H306 R588
Binding residue
(residue number reindexed from 1)		H234 R516
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.5.-
Gene Ontology
Molecular Function
GO:0003746 translation elongation factor activity
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0016787 hydrolase activity
GO:0043022 ribosome binding
Biological Process
GO:0006412 translation
GO:0006414 translational elongation
GO:0006417 regulation of translation
GO:0032790 ribosome disassembly
GO:0045727 positive regulation of translation
GO:0045948 positive regulation of translational initiation
GO:0070651 nonfunctional rRNA decay
GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay
GO:0072344 rescue of stalled ribosome
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:1990533 Dom34-Hbs1 complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5m1j, PDBe:5m1j, PDBj:5m1j
PDBsum5m1j
PubMed27995908
UniProtP32769|HBS1_YEAST Elongation factor 1 alpha-like protein (Gene Name=HBS1)

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