Structure of PDB 9bs4 Chain A Binding Site BS03

Receptor Information
>9bs4 Chain A (length=627) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DPSGYNPAKNNYHPVEDACWKPGQKVPYLAVARTFEKIEEVSARLRMVET
LSNLLRSVVALSPPDLLPVLYLSLNHLGPPQQGLALGVGDGVLLKAVAQA
TGRQLESVRAEAAEKGDVGLVAENSRPPPPLTASGVFSKFRDIARLTGSA
STAKKIDIIKGLFVACRHSEARFIARSLSGRLRLGLAEQSVLAALSQAVS
LTPPGQEFPPAMVDAGKGKTAEARKTWLEEQGMILKQTFCEVPDLDRIIP
VLLEHGLERLPEHCKLSPGIPLKPMLAHPTRGISEVLKRFEEAAFTCEYK
YDGQRAQIHALEGGEVKIFSRNQADNTGKYPDIISRIPKIKLPSVTSFIL
DTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGE
SLVREPLSRRRQLLRENFVETEGEFVFATSLDTKDIEQIAEFLEQSVKDS
CEGLMVKTLDVDATYEIAKRSHNWLKLKKDYDTLDLVVIGAYLGRGKRAG
RYGGFLLASYDEDSEELQAICKLGTGFSDEELEEHHQSLKALVLPSPRPY
VRIDGAVIPDHWLDPSAVWEVKCADLSLSPIYPAARGLVDSDKGISLRFP
RFIRVREDKQPEQATTSAQVACLYRKQ
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB9bs4 Structures of LIG1 uncover the mechanism of sugar discrimination against 5'-RNA-DNA junctions during ribonucleotide excision repair.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		R305 T415 G416 A418 S419 T420 R451 G453 A455 Q457 S458 Q636 T639 T640 K642 R643
Binding residue
(residue number reindexed from 1)		R44 T147 G148 A150 S151 T152 R183 G185 A187 Q189 S190 Q368 T371 T372 K374 R375
External links
PDB RCSB:9bs4, PDBe:9bs4, PDBj:9bs4
PDBsum9bs4
PubMed39159820
UniProtP18858|DNLI1_HUMAN DNA ligase 1 (Gene Name=LIG1)

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