Structure of PDB 9atn Chain A Binding Site BS03

Receptor Information
>9atn Chain A (length=98) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSARCAVCEGPGELCDLFFCTSCGHHYHGACLDTALTARKRAGWQCPECK
VCQACRKPGNDSKMLVCETCDKGYHTFCLKPPMEELPAHSWKCKACRV
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain9atn Chain A Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB9atn ASXLs binding to the PHD2/3 fingers of MLL4 provides a mechanism for the recruitment of BAP1 to active enhancers.
ResolutionN/A
Binding residue
(original residue number in PDB)		C244 C247
Binding residue
(residue number reindexed from 1)		C20 C23
Annotation score1
External links
PDB RCSB:9atn, PDBe:9atn, PDBj:9atn
PDBsum9atn
PubMed38849395
UniProtO14686|KMT2D_HUMAN Histone-lysine N-methyltransferase 2D (Gene Name=KMT2D)

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