Structure of PDB 9asq Chain A Binding Site BS03

Receptor Information
>9asq Chain A (length=916) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VWIRCTHSENYYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAK
AARPPWEPDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSAKARR
TGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEY
DDHEYIFEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKG
LELFSLFLFRDILELYDWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGK
EVLSMHQILLYLLRCSKALVPEEEIANMLQWEELEWQKYAEECKGMIVTN
PGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPAQLSYAGDPQYQKLW
KSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTVELSS
QGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQ
LAMTHPSHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINT
LINIMSRLGQDDPTPSRINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEG
GLATYRTAIVQNQHLAMLAKKLELDRFMLYAHGPDLCRESDLRHAMANCF
EALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLNYPLHPLQLQEPNTD
RQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTLGHNQ
RMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEEL
GMQEYAITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVC
FFPRLKEFILNQDWNDPKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSH
ARTYTVAVYFKGERIGCGKGPSIQQAEMGAAMDALEKYNFPQMAHQKRFI
ERKYRQELKEMRWERE
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain9asq Chain A Residue 1401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB9asq RNAi_protein_f1_SR
Resolution3.0 Å
Binding residue
(original residue number in PDB)		C561 H609 C676 H680
Binding residue
(residue number reindexed from 1)		C117 H165 C232 H236
Annotation score4
External links
PDB RCSB:9asq, PDBe:9asq, PDBj:9asq
PDBsum9asq
PubMed
UniProtQ9NRR4|RNC_HUMAN Ribonuclease 3 (Gene Name=DROSHA)

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