Structure of PDB 9aso Chain A Binding Site BS03

Receptor Information
>9aso Chain A (length=916) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VWIRCTHSENYYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAK
AARPPWEPVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSAKA
RRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVI
EYDDHEYIFEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCV
KGLELFSLFLFRDILELYDWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDG
GKEVLSMHQILLYLLRCSKALVPEEEIANMLQWEELEWQKYAEECKGMIV
TNPGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPAQLSYAGDPQYQK
LWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTVEL
SSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCL
LQLAMTHPSHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGI
NTLINIMSRLGQDDPTPSRINHNERLEFLGDAVVEFLTSVHLYYLFPSLE
EGGLATYRTAIVQNQHLAMLAKKLELDRFMLYAHGPDLCRESDLRHAMAN
CFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLNYPLHPLQLQEPN
TDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTLGH
NQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAE
ELGMQEYAITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMN
VCFFPRLKEFILNQDWNDPKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGP
SHARTYTVAVYFKGERIGCGKGPSIQQAEMGAAMDALEKYNFPQMAHQKR
FIERKYRQELKEMRWE
Ligand information
>9aso Chain E (length=71) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ugacugcaugcucccagguugagguaguagguuguauacagccuccuagc
uuuccuugggucuugcacuaa
.....<<<.<..<<<<<<..<<<.<<<.<<<<<<<..>>>>>>>.>>>.>
>>..>>>>>>.>.>>>.....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB9aso RNAi_protein_a2
Resolution2.9 Å
Binding residue
(original residue number in PDB)		W794 V798 R801 R836 E837 R914 R930 R938 K939 G941 I942 R1032 G1172 N1184 R1213 K1262 Q1266 L1270 R1273 S1293 H1294 R1296 Y1298 S1316 I1317 Q1318
Binding residue
(residue number reindexed from 1)		W352 V356 R359 R394 E395 R472 R488 R496 K497 G499 I500 R590 G730 N742 R771 K820 Q824 L828 R831 S851 H852 R854 Y856 S874 I875 Q876
External links
PDB RCSB:9aso, PDBe:9aso, PDBj:9aso
PDBsum9aso
PubMed
UniProtQ9NRR4|RNC_HUMAN Ribonuclease 3 (Gene Name=DROSHA)

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