Structure of PDB 9asn Chain A Binding Site BS03

Receptor Information
>9asn Chain A (length=915) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VWIRCTHSENYYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAK
AARPPWEPVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSAKA
RRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVI
EYDDHEYIFEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCV
KGLELFSLFLFRDILELYDWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDG
GKEVLSMHQILLYLLRCSKALVPEEEIANMLQWEELEWQKYAEECKGMIV
TNPGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPAQLSYAGDPQYQK
LWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTVEL
SSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCL
LQLAMTHPSHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGI
NTLINIMSRLGQDDPTPSRINHNERLEFLGDAVVEFLTSVHLYYLFPSLE
EGGLATYRTAIVQNQHLAMLAKKLELDRFMLYAHGPDLCRESDLRHAMAN
CFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLNYPLHPLQLQEPN
TDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTLGH
NQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAE
ELGMQEYAITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMN
VCFFPRLKEFILNQDWNDPKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGP
SHARTYTVAVYFKGERIGCGKGPSIQQAEMGAAMDALEKYNFPQMAHQKR
FIERKYRQELKEMRW
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain9asn Chain A Residue 1401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB9asn RNAi_protein_98
Resolution3.2 Å
Binding residue
(original residue number in PDB)		C561 H609 C676 H680
Binding residue
(residue number reindexed from 1)		C119 H167 C234 H238
Annotation score4
External links
PDB RCSB:9asn, PDBe:9asn, PDBj:9asn
PDBsum9asn
PubMed
UniProtQ9NRR4|RNC_HUMAN Ribonuclease 3 (Gene Name=DROSHA)

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