Structure of PDB 8xrf Chain A Binding Site BS03

Receptor Information

>8xrf Chain A (length=773) Species: 10498 (African swine fever virus BA71V) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

VDVDKYTRARNAGGKRAQDCMLLAAEGDSALSLLRTGLTLGKSNPSGPSF
DFCGMISLGGVIMNACKKVTNITTIMVRNEQLTNNKVLQGIVQVLGLDFN
CHYKTQEERAKLRYGCIVACVDQDLDGCGKILGLLLAYFHLFWPQLIIHG
FVKRLLTPLIRVYEKGKTMPVEFYYEQEFDAWAKKQTSLVNHTVKYYKGL
AAHDTHEVKSMFKHFDNMVYTFTLDDSAKELFHIYFGGESELRKRELCTG
VVPLTETQTQSIHSVRRIPCSLHLQVDTKAYKLDAIERQIPNFLDGMTRA
RRKILAGGVKCFASNNRERKVFQFGGYVADHMFYHHGDMSLNTSIIKAAQ
YYPGSSHLYPVFIGIGSFGSRHLGGKDAGSPRYISVQLASEFIKTMFPAE
DSWLLPYVFEDGQRAEPEYYVPVLPLAIMEYGANPSEGWKYTTWARQLED
ILALVRAYVDKDNPKHELLHYAIKHKITILPLRPSNYNFKGHLKRFGQYY
YSYGTYDISEQRNIITITELPLRVPTVAYIESIKKSSNRMTFIEEIIDYS
SSETIEILVKLPNSLNRIVEEFKETEEQDSIENFLRLRNCLHSHLNFVKP
KGGIIEFNSYYEILYAWLPYRRELYQKRLMREHAVLKLRIIMETAIVRYI
NESAELNLSHYEDEKEASRILSEHGFPPLNHTLIISPEFASIEELNQKAL
QGCYTYILSLQARELLIAAKTRRVEKIKKMQARLDKVEQLLQESPFPGAS
VWLEEIDAVEKAIIKGRNTQWKF

Ligand information

>8xrf Chain F (length=15) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

cgcgaatcgtcatcc

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8xrf The crystal structure of AsfvTopII in complex with G-DNA
Resolution	2.94 Å
Binding residue (original residue number in PDB)	V473 M475 N476 K479 K547 S657 R660 R799 Y800 P852 S853 E854 G855 K857 K952 S953 S954 H1012
Binding residue (residue number reindexed from 1)	V61 M63 N64 K67 K130 S240 R243 R382 Y383 P435 S436 E437 G438 K440 K535 S536 S537 H594

External links

PDB	RCSB:8xrf, PDBe:8xrf, PDBj:8xrf
PDBsum	8xrf
PubMed
UniProt	Q00942\|TOP2_ASFB7 DNA topoisomerase 2 (Gene Name=TOP)

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