Structure of PDB 8xak Chain A Binding Site BS03

Receptor Information

>8xak Chain A (length=501) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

CLSKEQESIIKLAENGHNIFYTGSAGTGKSILLREMIKVLKGIYGRENVA
VTASTGLAACNIGGITIHSFAGIGLGKGDADKLYKKVRRSRKHLRRWENI
GALVVDEISMLDAELLDKLDFIARKIRKNHQPFGGIQLIFCGDFFQLPPV
SKDPNRPTKFAFESKAWKEGVKMTIMLQKVFRQRGDVKFIDMLNRMRLGN
IDDETEREFKKLSRPLPDDEIIPAELYSTRMEVERANNSRLSKLPGQVHI
FNAIDGGALEDEELKERLLQNFLAPKELHLKVGAQVMMVKNLDATLVNGS
LGKVIEFMDPETYFCYEALTNDPSMPPEKLETWAENPSKLKAAMEREQIG
EPVSPLDSSVFDFMKRVVLENIKRKEQLMQTIHQNSAGKRRLPLVRFKAS
DMSTRMVLVEPEDWAIEDENEKPLVSRVQLPLMLAWSLSIHKSQGQTLPK
VKVDLRRVFEKGQAYVALSRAVSREGLQVLNFDRTRIKAHQKVIDFYLTL
S

Ligand information

Ligand ID

ALF

InChI

InChI=1S/Al.4FH/h;4*1H/q+3;;;;/p-4

InChIKey

UYOMQIYKOOHAMK-UHFFFAOYSA-J

SMILES

Software	SMILES
ACDLabs 10.04 CACTVS 3.341 OpenEye OEToolkits 1.5.0	F[Al-](F)(F)F

Formula

Al F4

Name

TETRAFLUOROALUMINATE ION

PDB chain

8xak Chain A Residue 1002 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8xak Eukaryotic Pif1 helicase unwinds G-quadruplex and dsDNA using a conserved wedge.
Resolution	3.5 Å
Binding residue (original residue number in PDB)	A260 E342 Q381 R417 G709 R734
Binding residue (residue number reindexed from 1)	A25 E107 Q146 R182 G445 R470
Annotation score	1

External links

PDB	RCSB:8xak, PDBe:8xak, PDBj:8xak
PDBsum	8xak
PubMed	39030241

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