Structure of PDB 8x5v Chain A Binding Site BS03

Receptor Information

>8x5v Chain A (length=892) Species: 1465 (Brevibacillus laterosporus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MAYTMGIDVGIASCGWAIVDLERQRIIDIGVRTFEEALAVPRREARSSRR
RLRRKKHRIERLKHMFVRNGLAVDIQHLEQTLRSQNEIDVWQLRVDGLDR
MLTQKEWLRVLIHLAQRRGFQSNRKTEDGQVLVNVTENDRLMEEKDYRTV
AEMMVKDEKFSDHKRNKNGNYHGVVSRSSLLVEIHTLFETQRQHHNSLAS
KDFELEYVNIWSAQRPVATKDQIEKMIGTCTFLPKEKRAPKASWHFQYFM
LLQTINHIRITNVQGTRSLNKEEIEQVVNMALTKSKVSYHDTRKILDLSE
EYQFVGLDYGKEDEKKKVESKETIIKLDDYHKLNKIFNEVELAKGETWEA
DDYDTVAYALTFFKDDEDIRDYLQNKYKDSKNRLVKNLANKEYTNELIGK
VSTLSFRKVGHLSLKALRKIIPFLEQGMTYDKACQAAGFDFQGISKKKRS
VVLPVIDQISNPVVNRALTQTRKVINALIKKYGSPETIHIETGGGSGGYI
TKYLSHFISTNLEFSPSDKKKKVVNTSGRITSHLRSRWGLENDLHHAMDA
IVIAVTSDSFIQQVTNYYKRKERFPLPWKFFREEVIARLSPNPKEQIEAL
PNHFYSEDELADLQPIFVSRMPKRSITGEAHQAQFRRVVGKTKEGKNITA
KKTALVDISYDKNGDFNMYGRETDPATYEAIKERYLEFGGNVKKAFSTDL
HKPKKDGTKGPLIKSVRIMENKTLVHPVNKGKGVVYNSSIVRTDVFQRKE
KYYLLPVYVTDVTKGKLPNKVIVAKKGYHDWIEVDDSFTFLFSLYPNDLI
FIRQNPKKKISLKKRIESHSISDSKEVQEIHAYYKGVDSSTAAIEFIIHD
GSYYAKGVGVQNLDCFEKYQVDILGNYFKVKGEKRLELETSD

Ligand information

>8x5v Chain D (length=8) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

tttccaaa

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8x5v Structure and engineering of Brevibacillus laterosporus Cas9.
Resolution	2.0 Å
Binding residue (original residue number in PDB)	K830 N905 K906 T907 N921 S922 S923 I924 Y942 D1022 S1023 S1024
Binding residue (residue number reindexed from 1)	K646 N721 K722 T723 N737 S738 S739 I740 Y758 D838 S839 S840

External links

PDB	RCSB:8x5v, PDBe:8x5v, PDBj:8x5v
PDBsum	8x5v
PubMed	38961195

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