Structure of PDB 8ufy Chain A Binding Site BS03

Receptor Information
>8ufy Chain A (length=358) Species: 1377 (Aerococcus viridans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
YNAPSEIKYIDVVNTYDLEEEASKVVPHGGFNYIAGASGDEWTKRANDRA
WKHKLLYPRLAQDVEAPDTSTEILGHKIKAPFIMAPIAAHGLAHTTKEAG
TARAVSEFGTIMSISAYSGATFEEISEGLNGGPRWFQIYMAKDDQQNRDI
LDEAKSDGATAIILTADSTVSGNRDRDVKNKFVYPFGMPIVQRYLRGTNI
YGASKISPRDIEEIAAHSGLPVFVKGIQHPEDADMAIKAGASGIWVSNHG
ARQLYEAPGSFDTLPAIAERVNKRVPIVFDSGVRRGEHVAKALASGADVV
ALGRPVLFGLALGGWQGAYSVLDYFQKDLTRVMQLTGSQNVEDLKGLDLF
DNPYGYEY
Ligand information
Ligand IDPYR
InChIInChI=1S/C3H4O3/c1-2(4)3(5)6/h1H3,(H,5,6)
InChIKeyLCTONWCANYUPML-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.385CC(=O)C(O)=O
OpenEye OEToolkits 1.7.6CC(=O)C(=O)O
ACDLabs 12.01O=C(C(=O)O)C
FormulaC3 H4 O3
NamePYRUVIC ACID
ChEMBLCHEMBL1162144
DrugBankDB00119
ZINCZINC000001532517
PDB chain8ufy Chain A Residue 405 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8ufy An engineered lactate oxidase based electrochemical sensor for continuous detection of biomarker lactic acid in human sweat and serum
Resolution1.2 Å
Binding residue
(original residue number in PDB)		Y124 R181 Y215
Binding residue
(residue number reindexed from 1)		Y117 R174 Y201
Annotation score5
External links
PDB RCSB:8ufy, PDBe:8ufy, PDBj:8ufy
PDBsum8ufy
PubMed39149041
UniProtQ44467|LOX_AERVM L-lactate oxidase

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