Structure of PDB 8r0z Chain A Binding Site BS03

Receptor Information
>8r0z Chain A (length=234) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GAMGSMERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLS
VAYKNVVGGQRAAWRVLSSIEQKSNESEEKGPEVREYREKVETELQGVCD
TVLGLLDSHLIKEAGDAESRVFYLKMKGDYYRYLAEVATGDDKKRIIDSA
RSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHYEIANSPEEAISLAKTT
FDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWT
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain8r0z Chain A Residue 304 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8r0z Fragment-Based Interrogation of the 14-3-3/TAZ Protein-Protein Interaction.
Resolution1.2 Å
Binding residue
(original residue number in PDB)		E35 E110
Binding residue
(residue number reindexed from 1)		E40 E113
Annotation score4
External links
PDB RCSB:8r0z, PDBe:8r0z, PDBj:8r0z
PDBsum8r0z
PubMed39172504
UniProtP31947|1433S_HUMAN 14-3-3 protein sigma (Gene Name=SFN)

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