Structure of PDB 8pw0 Chain A Binding Site BS03

Receptor Information
>8pw0 Chain A (length=137) Species: 1299 (Deinococcus radiodurans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TLSPSAEDYLKHLYGLGQSGKVSTQALAAALGVAPASVTGMLRKLTEQGL
VSHAPYQGARLTAEGERVALEVLRHHRLLELFLHRALGVPLDEVHDEAEA
LEHALSERLEARIAAWLGDPTHDPHGDPIPTLEGELP
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain8pw0 Chain A Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8pw0 Metal ion activation and DNA recognition by the Deinococcus radiodurans manganese sensor DR2539.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		E74 H78 E110 E113
Binding residue
(residue number reindexed from 1)		E71 H75 E107 E110
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0046914 transition metal ion binding
GO:0046983 protein dimerization activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:8pw0, PDBe:8pw0, PDBj:8pw0
PDBsum8pw0
PubMed38652591
UniProtQ9RRF3

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