Structure of PDB 8pkb Chain A Binding Site BS03

Receptor Information

>8pkb Chain A (length=296) Species: 1280 (Staphylococcus aureus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MLLGSHVSMSGKKMLEGSAIEAHEYGETTFMIYTGAPQNTRRKSIEDLNI
TKGHEVMEKYGLSNIVVHAPYIINIANTTKPETFNLGVDFLQQEIERTQA
IGAKDIVLHPGAHVGAGVDAGINKIIEGLNEVLTNDNNVRIALETMAGKG
TEIGRSFEELARIIDGVHNNERLSVCFDTCHTHDAGYNVKEDFDGVLNEF
DKIIGVDRIKVVHVNDSKNDRGAQKDRHENIGFGYIGFDALNYIVHHDSF
KDIPKILETPYVGEDKKNKKPPYKLEIEMLKQQHFDPELKNKVMQQ

Ligand information

Ligand ID

InChI

InChI=1S/Zn/q+2

InChIKey

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Name

ZINC ION

PDB chain

8pkb Chain A Residue 303 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8pkb Octahedrally coordinated iron in the catalytic site of endonuclease IV from Staphylococcus aureus
Resolution	1.9 Å
Binding residue (original residue number in PDB)	H181 D226 H228
Binding residue (residue number reindexed from 1)	H181 D226 H228
Annotation score	4

Gene Ontology

	Molecular Function
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity
GO:0004519	endonuclease activity
GO:0008081	phosphoric diester hydrolase activity
GO:0008270	zinc ion binding
GO:0008833	deoxyribonuclease IV (phage-T4-induced) activity
GO:0046872	metal ion binding

	Biological Process
GO:0006281	DNA repair
GO:0006284	base-excision repair

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Molecular Function

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Biological Process

External links

PDB	RCSB:8pkb, PDBe:8pkb, PDBj:8pkb
PDBsum	8pkb
PubMed
UniProt	Q6GGE2\|END4_STAAR Probable endonuclease 4 (Gene Name=nfo)

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