Structure of PDB 8j9q Chain A Binding Site BS03

Receptor Information
>8j9q Chain A (length=73) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GHMKLCTFTITQKEFMNQHWYHCHTCKMVDGVGVCTVCAKVCHKDHEISY
AKYGSFFCDCGAKEDGSCLALVK
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8j9q Chain A Residue 1803 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8j9q Crystal structure of UBR box of UBR4 apo
Resolution2.18 Å
Binding residue
(original residue number in PDB)		C1682 H1699 H1702
Binding residue
(residue number reindexed from 1)		C26 H43 H46
Annotation score4
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:8j9q, PDBe:8j9q, PDBj:8j9q
PDBsum8j9q
PubMed38030679
UniProtQ5T4S7|UBR4_HUMAN E3 ubiquitin-protein ligase UBR4 (Gene Name=UBR4)

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