Structure of PDB 8i54 Chain A Binding Site BS03

Receptor Information
>8i54 Chain A (length=1113) Species: 1408323 (Lachnospiraceae bacterium MA2020) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
YESLTKQYPVSKTIRNELIPIGKTLDNIRQNNILESDVKRKQNYEHVKGI
LDEYHKQLINEALDNCTLPSLKIAAEIYLKNQKEVSDREDFNKTQDLLRK
EVVEKLKAHENFTKIGKKDILDLLEKLPSISEDDYNALESFRNFYTYFTS
YNKVRENLYSDKEKSSTVAYRLINENFPKFLDNVKSYRFVKTAGILADGL
GEEEQDSLFIVETFNKTLTQDGIDTYNSQVGKINSSINLYNQKNQKANGF
RKIPKMKMLYKQILSDREESFIDEFQSDEVLIDNVESYVKNDLAKTAMSN
IVFENWRTFDDLLNQEYDLANENKKKDDSCNLIENYIHQISDDIENILAK
NRKAVKAIKDFLDSIKVLERELKLINSSGQELEKVELKQVDSLYNMTRNY
LTKKPFSTEKVKLNFNRSTLLNGWDRNKETDNLGVLLLKDGKYYLGIMNT
SANKAFVNPPVAKTEKVFKKVDYKLLPVPNQMLPKVFFAKSNIDFYNPSS
EIYSNYKKGTHKKGNMFSLEDCHNLIDFFKESISKHEDWSKFGFKFSDTA
SYNDISEFYREVEKQGYKLTYTDIDETYINDLIERNELYLFQIYNKDFSM
YSKGKLNLHTLYFMMLFDQRNIDDVVYKLNGEAEVFYRPASISEDELIIH
KAGEEIKNKNPNRARTKETSTFSYDIVKDKRYSKDKFTLHIPITMNFGVD
EVKRFNDAVNSAIRIDENVNVIGIDRGERNLLYVVVIDSKGNILEQISLN
SIINKEYDIETDYHALLDEREGGRDKARKDWNTVENIRDLKAGYLSQVVN
VVAKLVLKYNAIICLEDLNFGFKRGRQKVEKQVYQKFEKMLIDKLNYIDK
SREQTSPKELGGALNALQLTSKFKSFKELGKQSGVIYYVPAYLTSKIDPT
TGFANLFYMKCENVEKSKRFFDGFDFIRFNALENVFEFGFDYRSFTQRAC
GINSKWTVCTNGERIIKYRNPDKNNMFDEKVVVVTDEMKNLFEQYKIPYE
DGRNVKDMIISNEEAEFYRRLYRLLQQTLQMRNSTSDGTRDYIISPVKNK
REAYFNSELSDGSVPKDADANGAYNIARKGLWVLEQIRQKSEGEKINLAM
TNAEWLEYAQTHL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8i54 Structures of apo Cas12a and its complex with crRNA and DNA reveal the dynamics of ternary complex formation and target DNA cleavage.
Resolution3.95 Å
Binding residue
(original residue number in PDB)
L126 N145 Q571
Binding residue
(residue number reindexed from 1)
L124 N143 Q481
External links