Structure of PDB 8hip Chain A Binding Site BS03

Receptor Information
>8hip Chain A (length=647) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SVLVFEISSKMKMIEKKLEANTVHVLRLELDQSFILDLTKVAAEIVDSSK
YSKEDGVILEVTVSNGRDSFLLKLPTVYPNLKLYTDGKLLNPLVEQDFHF
HQNLIVTVQSRLNADIDYRLHVTHLDRAQYDFLKFKTGQTTKTLSNQKLT
FVKPIGFFLNCSEQNISQFHVTLYSEDDICANLITVPANESIYDRSVISD
KTHNRRVLSFTKRADIFFTETEISMFKSFRIFVFIAPDDSGCSTNTSRKS
FNEKKKISFEFKKLENQSYAVPTALMMIFLTTPCLLFLPIVINIIKNSRS
LHGQMLQYPVAIILPVLMHTAIEFHKWTTSTMANRDEMCFHNHACARPLG
ELRAWNNIITNIGYTLYGAIFIVLSICRRGSHVFGTYECTLLDVTIGVFM
VLQSIASATYHICPSDVAFQFDTPCIQVICGLLMVRQWFVRHESPSPAYT
NILLVGVVSLNFLISAFSKTSYVRFIIAVIHVIVVGSICLAKERSLGSEK
LKTRFFIMAFSMGNFAAIVMYLTLSAFHLNQIATYCFIINCIMYLMYYGC
MKVLHSERITSKAKLCGALSLLAWAVAGFFFFQDDTDWTRSAAASRALNK
PCLLLGFFGSHDLWHIFGALAGLFTFIFVSFVDDDLINTRKTSINIF
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8hip Chain A Residue 803 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8hip Structure of dsRNA transporter at 2.77 Angstroms resolution.
Resolution2.77 Å
Binding residue
(original residue number in PDB)		H540 D551 H740 H744
Binding residue
(residue number reindexed from 1)		H411 D422 H611 H615
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:8hip, PDBe:8hip, PDBj:8hip
PDBsum8hip
PubMed38664565
UniProtQ9GZC8|SID1_CAEEL Systemic RNA interference defective protein 1 (Gene Name=sid-1)

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