Structure of PDB 8h4x Chain A Binding Site BS03

Receptor Information
>8h4x Chain A (length=330) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TLSNASGTFAIRLLKILCQDNPSHNVFCSPVSISSALAMVLLGAKGNTAT
QMAQALSLNTEEDIHRAFQSLLTYLLRTANRLFGEKTCQFLSTFKESCLQ
FYHAELKELSFIRAAEESRKHINTWVSKKTEGKIEELLPGSSIDAETRLV
LVNAIYFKGKWNEPFDETYTREMPFKINQEEQRPVQMMYQEATFKLAHVG
EVRAQLLELPYARKELSLLVLLPDDGVELSTVEKSLTFEKLTAWTKPDCM
KSTEVEVLLPKFKLQEDYDMESVLRHLGIVDAFQQGKADLSAMSAERDLC
LSKFVHKSFVEVNEEGTEAAAASAVVIAAA
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8h4x Chain A Residue 404 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8h4x Expression, purification and crystallization of cleaved Serpin B9
Resolution1.93 Å
Binding residue
(original residue number in PDB)		H208 D234
Binding residue
(residue number reindexed from 1)		H198 D224
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004867 serine-type endopeptidase inhibitor activity
Cellular Component
GO:0005615 extracellular space

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Molecular Function
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Cellular Component
External links
PDB RCSB:8h4x, PDBe:8h4x, PDBj:8h4x
PDBsum8h4x
PubMed
UniProtP50453|SPB9_HUMAN Serpin B9 (Gene Name=SERPINB9)

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