Structure of PDB 8ehe Chain A Binding Site BS03

Receptor Information
>8ehe Chain A (length=353) Species: 28112 (Tannerella forsythia) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QTQTDPLYPQQYYLNNTGQFGGTNNIDINAPEAWNITTGNTSVRVAVIDD
GVEAHEDMAGRLLPGFTARSSAENPNRNGAPNNTNPPSTPYPNDNDSPIG
HGQACAGIIAANHNGMGIRGIAPQVRIIPINIFNDWFIDQIFNGYYWMDF
VRYRETVQDIANAIDAAWDTHSADILSNSWGYGTTPNSADAIVAAINRAR
TQGRDGRGCPVIFASGNAWGQQGVTDVAFPGNVEGVITVGAIDNRGNIWN
YSQRGASMDLVAPSGGVPGNIVTTDRMGNFGYNNTNYTNTFNGTSAACPQ
VAGVAALMLSVRPDLTEAQVRTILQNTARDLGSAGFDNTYGYGLVDAHAA
VAP
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain8ehe Chain A Residue 604 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8ehe A unique network of attack, defence and competence on the outer membrane of the periodontitis pathogen Tannerella forsythia.
Resolution1.1 Å
Binding residue
(original residue number in PDB)		D512 L513 S515 G517 D519
Binding residue
(residue number reindexed from 1)		D330 L331 S333 G335 D337
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
GO:0008236 serine-type peptidase activity
Biological Process
GO:0006508 proteolysis

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:8ehe, PDBe:8ehe, PDBj:8ehe
PDBsum8ehe
PubMed36755705
UniProtA0A0A7KVG3

[Back to BioLiP]