Structure of PDB 8eey Chain A Binding Site BS03

Receptor Information
>8eey Chain A (length=1544) Species: 45657 (Desulfonema ishimotonii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TTTMKISIEFLEPFRMTKWQESTRRNKNNKEFVRGQAFARWHRNKKDNTK
GRPYITGTLLRSAVIRSAENLLTLSDGKISEKTCCPGKFDTEDKDRLLQL
RQRSTLRWTDKNPCPDNAETYCPFCELLGRSWRFRIHFGNLSLPGKPDFD
GPKAIGSQRVLNRVDFKSGKAHDFFKAYEVDHTRFPRFEGEITIDNKVSA
EARKLLCDSLKFTDRLCGALCVIRFNLAEKTAEQIISILDDNKKTEYTRL
LADAIRSLRRSSKLVAGLPKDHDGKDDHYLWDIGKSVTIRQILTTSADTK
ELKNAGKWREFCEKLGEALYLKSKDMSGGLKITRRILGDAEFHGKPDRLE
KSRSVSIGSVLKETVVCGELVAKTPFFFGAIDEDAKQTALQVLLTPDNKY
RLPRSAVRGILRRDLQTYFDSPCNAELGGRPCMCKTCRIMRGITVMDARS
EYNAPPEIRHRTRINPFTGTVAEGALFNMEVAPEGIVFPFQLRYRGSEDG
LPDALKTVLKWWAEGQAFMSGAASTGKGRFRMENAKYETLDLSDENQRND
YLKNWGWRDEKGLEELKKRLNSGLPEPGNYRDPKWHEINVSIEMASPFIN
GDPIRAAVDKRGTAVVTFVKYKAEGEEAKPVCAYKAESFRGVIRSAVARI
HMEDGVPLTELTHSDCECLLCQIFGSEYEAGKIRFEDLVFESDPEPVTFD
HVAIDRFTGGAADKKKFDDSPLPGSPARPLMLKGSFWIRRDVLEDEEYCK
ALGKALADVNNGLYPLGGKSAIGYGQVKSLGIKGDDKRISRLMNVAVPEK
PKTDAEVRIEAEKVYYPHYFVEPHKKVEREEKPCGHQKFHEGRLTGKIRC
KLITKTPLIVPDTSNDDFFRPEYHKSYAFFRLHKQIMIPGSELRGMVSSV
YETVTNSCFRIFDETKRLSWRMDADHQNVLQDFLPGRVTADGKHIQKFSE
TARVPFYDKTQKHFDILDEQEIAGEKPVRMWVKRFIKRLSLVDPAKHPQK
KQDNKWKRRKEGIATFIEQKNGSYYFNVVTNNGCTSFHLWHKPDNFDQEK
LEGIQNGEKLDCWVRDSRYQKAFQEIPENDPDGWECKEGYLHVVGPSKVE
FSDKKGDVINNFQGTLPSVPNDWKTIRTNDFKNRKRKNEPVFCCEDDKGN
YYTMAKYCETFFFDLKENEEYEIPEKARIKYKELLRVYNNNPQAVPESVF
QSRVARENVEKLKSGDLVYFKHNEKYVEDIVPVRISRTVDDRMIGKRMSA
DLRPCHGDWVEDGDLSALNAYPEKRLLLRHPKGLCPACRLFGTGSYKGRV
RFGFASLENDPEWLIPGKNPGDPFHGGPVMLSLLERPRPTWSIPGSDNKF
KVPGRKFYVHHHAWKTIKDGNHPTTGKAIEQSPNNRTVEALAGGNSFSFE
IAFENLKEWELGLLIHSLQLEKGLAHKLGMAKSMGFGSVEIDVESVRLRK
DWKQWRNGNSEIPNWLGKGFAKLKEWFRDELDFIENLKKLLWFPEGDQAP
RVCYPMLRKKDDPNGNSGYEELKDGEFKKEDRQKKLTTPWTPWA
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8eey Chain A Residue 2001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8eey RNA-activated protein cleavage with a CRISPR-associated endopeptidase.
Resolution2.53 Å
Binding residue
(original residue number in PDB)		C86 C123 C126
Binding residue
(residue number reindexed from 1)		C85 C122 C125
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0051607 defense response to virus

View graph for
Biological Process
External links
PDB RCSB:8eey, PDBe:8eey, PDBj:8eey
PDBsum8eey
PubMed36423276
UniProtA0A401FT36

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