Structure of PDB 8e7f Chain A Binding Site BS03

Receptor Information
>8e7f Chain A (length=614) Species: 615 (Serratia marcescens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
YQDPGRLGAPDSWKTAEFNRQWGLEAISAEFAYARGYTGKGITIGVIDNA
ILSHSEFSGKLTRLDNGSYNFSYDKQDNMSFGDHGTHVAGIAAAKRDGAG
MHGVAFDADIIGTKLNDYGNRNGREELIQSAARVINNSWGIAPDIRRDAK
GDIIWLPNGRPDYVAFVKSEVIAEMMRSKSSVEWGSEQPVPTGGHSAMST
LLRAARHGKLIVFSAGNYNNYNIPEAQKSLPYAFPDVLNNYLIVTNLSDE
NQLSVSSTSCGQTASYCVSAPGSDIYSTVGRLESNTGGAVNREAYNKGEL
SLNPGYGNKSGTSMAAPHVTGVAAVLMQRFPYMSADQISAVIKTTATDLG
VAGIDNLFGWGRVNLRDAINGPKMFITKEDIPQEYYVPGSYSEKQFVVNI
PGLGNIVEPGTPVERRCTSSECSFDSWSNDISGHGGLTKTGAGTLALLGN
NTYRGDTWVKQGVLAIDGSVASNVYIENSGTLSGEGTVGAFRAARSGSVA
PGNGIGTLHVLHDAIFDRGSQYNVEVADNGRSDKIAARRAFLNGGSVNVS
LERSQNLLSQNEAQSLLGNKYTILTTTDGVTGRFENANPSYPFVKVALDY
RGNDVGLGITRTDA
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain8e7f Chain A Residue 713 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8e7f Crystal structure of a subtilisin-like autotransporter passenger domain reveals insights into its cytotoxic function.
Resolution2.0 Å
Binding residue
(original residue number in PDB)
P529 G532 E553 D561
Binding residue
(residue number reindexed from 1)
P501 G504 E525 D533
Annotation score4
Enzymatic activity
Enzyme Commision number 3.4.21.-
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
GO:0008236 serine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function

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Biological Process
External links
PDB RCSB:8e7f, PDBe:8e7f, PDBj:8e7f
PDBsum8e7f
PubMed36859523
UniProtP09489|PRTS_SERMA Extracellular serine protease

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