Structure of PDB 8dwj Chain A Binding Site BS03

Receptor Information
>8dwj Chain A (length=339) Species: 2681598 (Escherichia phage T4) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SIPWIDNEFAYRALAHLPKFTQVNNSSTFKLRFRCPVCGDSKTDQNKARG
WYYGDNNEGNIHCYNCNYHAPIGIYLKEFEPDLYREYIFEIRKEKGKSRP
IEKPKELPKQPEKKIIKSLPSCVRLDKLAEDHPIIKYVKARCIPKDKWKY
LWFTTEWPKLVNSIAPGTYKKEISEPRLVIPIYNANGKAESFQGRALKKD
APQKYITIEAYPEATKIYGVERVKDGDVYVLEGPIDSLFIENGIAITGGQ
LDLEVVPFKDRRVWVLDNEPRHPDTIKRMTKLVDAGERVMFWDKSPWKSK
DVNDMIRKEGATPEQIMEYMKNNIAQGLMAKMRLSKYAK
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8dwj Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8dwj Structural basis of the T4 bacteriophage primosome assembly and primer synthesis.
Resolution3.9 Å
Binding residue
(original residue number in PDB)		C37 C40 C65
Binding residue
(residue number reindexed from 1)		C35 C38 C63
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.7.-
Gene Ontology
Molecular Function
GO:0003896 DNA primase activity
GO:0016740 transferase activity
GO:0046872 metal ion binding
Biological Process
GO:0006260 DNA replication
GO:0006269 DNA replication, synthesis of primer
GO:0039693 viral DNA genome replication

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:8dwj, PDBe:8dwj, PDBj:8dwj
PDBsum8dwj
PubMed37474605
UniProtP04520|PRIM_BPT4 DNA primase (Gene Name=61)

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