Structure of PDB 8dqx Chain A Binding Site BS03

Receptor Information
>8dqx Chain A (length=497) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VVREEDKLWTVKYAPTNLQQVCGNKGSVMKLKNWLANWENSKKNSFKHAG
KDGSGVFRAAMLYGPPGIGKTTAAHLVAQELGYDILEQNASDVRSKTLLN
AGVKNALDNMSVVGYFKHNEEAQNLNGKHFVIIMDEVDGMSGGDRGGVGQ
LAQFCRKTSTPLILICNERNLPKMRPFDRVCLDIQFRRPDANSIKSRLMT
IAIREKFKLDPNVIDRLIQTTRGDIRQVINLLSTISTTTKTINHENINEI
SKAWEKNIALKPFDIAHKMLDGQIYSDIGSRNFTLNDKIALYFDDFDFTP
LMIQENYLSTRPSVLKPGQSHLEAVAEAANCISLGDIVEKKIRSSEQLWS
LLPLHAVLSSVYPASKVAGHMAGRINFTAWLGQNSKSAKYYRLLQEIHYH
TRLGTSTDKIGLRLDYLPTFRKRLLDPFLKQGADAISSVIEVMDDYYLTK
EDWDSIMEFFVGPDVTTAIIKKIPATVKSGFTRKYNSMTHPVAIYRT
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8dqx Multistep loading of a DNA sliding clamp onto DNA by replication factor C.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		N459 F552 F666 G671 S674 K675 R681
Binding residue
(residue number reindexed from 1)		N170 F263 F377 G382 S385 K386 R392
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003689 DNA clamp loader activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0000278 mitotic cell cycle
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0006271 DNA strand elongation involved in DNA replication
GO:0006272 leading strand elongation
GO:0006281 DNA repair
GO:0006298 mismatch repair
GO:0051301 cell division
Cellular Component
GO:0005634 nucleus
GO:0005663 DNA replication factor C complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8dqx, PDBe:8dqx, PDBj:8dqx
PDBsum8dqx
PubMed35939393
UniProtP38630|RFC1_YEAST Replication factor C subunit 1 (Gene Name=RFC1)

[Back to BioLiP]