Structure of PDB 8d2k Chain A Binding Site BS03 |
| >8d2k Chain A (length=1105) Species: 351607 (Acidothermus cellulolyticus 11B)
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GTVPVTWRLGVDVGERSIGLAAVSYEEDKPKEILAAVSWIHDGGVGDERS
GASRLALRGMARRARRLRRFRRARLRDLDMLLSELGWTPLPDKNVSPVDA
WLARKRLAEEYVVDETERRRLLGYAVSHMARHRGWRNPWTTIKDLKNLPQ
PSDSWERTRESLEARYSVSLEPGTVGQWAGYLLQRAPGIRLNPTQQSLSN
ATAFETRLRQEDVLWELRCIADVQGLPEDVVSNVIDAVFCQKRPSVPAER
IGRDPLDPSQLRASRACLEFQEYRIVAAVANLRIRDGSGSRPLSLEERNA
VIEALLAQTERSLTWSDIALEILKLPNESDLTSVPEEDGPSSLAYSQFAP
FDETSARIAEFIAKNRRKIPTFAQWWQEQDRTSRSDLVAALADNSIAGLL
VHLPDAELEALEGLALPSGRVAYSRLTLSGLTRVMRDDGVDVHNARKTCF
GVDDNWRPPLPALHEATGHPVVDRNLAILRKFLSSATMRWGPPQSIVVEL
ARGASESRERQAEEEAARRAHRKANDRIRAELRASGLSDPSPADLVRARL
LELYDCHCMYCGAPISWENSELDHIVPRTDGGSNRHENLAITCGACNKEK
GRRPFASWAETSNRVQLRDVIDRVQKLKYSGNMYWTRDEFSRYKKSVVAR
LKRRTSDPEVIQSIESTGYAAVALRDRLLSYGEKNGVAQVAVFRGGVTAE
ARRWLDISIERLFSRVAIFAQSTSTKRLDRRHHAVDAVVLTTLTPGVAKT
LADARSRRVSASTEEPQSPAYRQWKESCSGLGDLLISTAARDSIAVAAPL
RLRPTGALHEETLRAFSEHTVGAAWKGAELRRIVEPEVYAAFLALTDPGG
RFLKVSPSEDVLPADENRHIVLSDRVLGPRDRVKLFPDDRGSIRVRGGAA
YIASFHHARVFRWGSSHSPSFALLRVSLADLAVAGLLRDGVDVFTAELPP
WTPAWRYASIALVKAVESGDAKQVGWLVPGDELDFGPEGVTTAAGDLSMF
LKYFPERHWVVTGFEDDKRINLKPAFLSAEQAEVLRTERSDRPDTLTEAG
EILAQFFPRCWRATVAKVLCHPGLTVIRRTALGQPRWRRGHLPYSWRPWS
ADPWS |
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| PDB | 8d2k Coupled catalytic states and the role of metal coordination in Cas9 |
| Resolution | 2.43 Å |
Binding residue
(original residue number in PDB) | W141 N143 W145 R219 V258 R262 I263 G264 R274 N293 R295 S345 V346 E349 S435 G436 R437 D458 H460 D471 N472 R474 R519 R535 R564 E588 L589 D590 H591 R595 N614 E682 Y686 V689 G763 A799 |
Binding residue
(residue number reindexed from 1) | W135 N137 W139 R207 V246 R250 I251 G252 R262 N281 R283 S333 V334 E337 S418 G419 R420 D441 H443 D454 N455 R457 R502 R518 R547 E571 L572 D573 H574 R578 N597 E665 Y669 V672 G746 A770 |
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| Enzyme Commision number |
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