Structure of PDB 8c8q Chain A Binding Site BS03

Receptor Information
>8c8q Chain A (length=537) Species: 4896 (Schizosaccharomyces pombe) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NSWWTYVNRWIFSTNAKDIAILYLLFGLVSGIIGSVFSFIIRMELSAPGS
QFLSGNGQLYNVAISAHGILMIFFFIIPALFGAFGNYLVPLMIGAPDVAY
PRVNNFTFWLLPPALMLLLISALTEEGPGGGWTVYPPLSSITSHSGPAID
LAILSLQLTGISSTLGSVNLIATMINMRAPGLSLYQMPLFAWAIMITSIL
LLLTLPVLAGGLFMLFSDRNLNTSFYAPEGGGDPVLYQHLFWFFGHPEVY
ILIMPAFGVVSHIIPSLAHKPIFGKEGMLWAMLSIALLGLMVWSHHLFTV
GLDVDTRAYFSAATMVIAIPTGIKIFSWLATLTGGAIQWSRVPMLYAIGF
LILFTIGGLTGVILSNSVLDIAFHDTYFVVAHFHYVLSMGALFGLCGAYY
YWSPKMFGLMYNETLASIQFWILFIGVNIVFGPQHFLGLNGMPRRIPDYP
EAFVGWNFVSSIGSVISILSLFLFMYVMYDQFTSNRVVKTNPYLIPSYFD
DNVIFVNEKLGVAQSIEWLLHSPVHEHAFNTLPTKSI
Ligand information
Ligand IDCU
InChIInChI=1S/Cu/q+2
InChIKeyJPVYNHNXODAKFH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Cu+2]
CACTVS 3.341[Cu++]
FormulaCu
NameCOPPER (II) ION
ChEMBL
DrugBankDB14552
ZINC
PDB chain8c8q Chain A Residue 603 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8c8q Cryo-EM structure and function of S. pombe complex IV with bound respiratory supercomplex factor.
Resolution3.36 Å
Binding residue
(original residue number in PDB)		H247 H296 H297
Binding residue
(residue number reindexed from 1)		H246 H295 H296
Annotation score1
Enzymatic activity
Enzyme Commision number 7.1.1.9: cytochrome-c oxidase.
Gene Ontology
Molecular Function
GO:0004129 cytochrome-c oxidase activity
GO:0020037 heme binding
Biological Process
GO:0009060 aerobic respiration
Cellular Component
GO:0016020 membrane
GO:0045277 respiratory chain complex IV

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8c8q, PDBe:8c8q, PDBj:8c8q
PDBsum8c8q
PubMed36797353
UniProtP07657|COX1_SCHPO Cytochrome c oxidase subunit 1 (Gene Name=cox1)

[Back to BioLiP]