Structure of PDB 8bsg Chain A Binding Site BS03

Receptor Information
>8bsg Chain A (length=584) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EAHKSEIAHRFNDVGEEHFIGLVLITFSQYLQKCPYEEHAKLVKEVTDLA
KACVADESAANCDKSLHDIFGDKICALPSLRDTYGDVADCCEKKEPERNE
CFLHHKDDKPDLPPFARPEADVLCKAFHDDEKAFFGHYLYEVARRHPYFY
APELLYYAQKYKAILTECCEAADKGACLTPKLDALKEKALISAAQERLRC
ASIQKFGDRAYKAWALVRLSQRFPKADFTDISKIVTDLTKVHKECCHGDL
LECADDRADLAKYMCEHQETISSHLKECCDKPILEKAHCIYGLHNDETPA
GLPAVAEEFVEDKDVCKNYEEAKDLFLGKFLYEYSRRHPDYSVVLLLRLG
KAYEATLKKCCATDDPHACYAKVLDEFQPLVDEPKNLVKQNCELYEQLGD
YNFQNALLVRYTKKVPQVSTPTLVEISRSLGKVGSKCCKHPEAERLPCVE
DYLSVVLNRLCVLHEKTPVSEKVTKCCSESLVDRRPCFSALGPDETYVPK
EFNAETFTFHADICTLPETERKIKKQTALVELVKHKPHATNDQLKTVVGE
FTALLDKCCSAEDKEACFAVEGPKLVESSKATLG
Ligand information
Ligand IDPOG
InChIInChI=1S/C21H44O8/c1-15(23)9-24-17(3)11-26-19(5)13-28-21(7)14-29-20(6)12-27-18(4)10-25-16(2)8-22/h15-23H,8-14H2,1-7H3/t15-,16?,17?,18?,19?,20?,21?/m1/s1
InChIKeyOWRNLGZKEZSHGO-QAWAPDBNSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C[C@H](CO)OC[C@@H](C)OC[C@@H](C)OC[C@@H](C)OC[C@@H](C)OC[C@H](C)OC[C@@H](C)O
CACTVS 3.341C[C@@H](O)COC(C)COC(C)COC(C)COC(C)COC(C)COC(C)CO
OpenEye OEToolkits 1.5.0CC(CO)OCC(C)OCC(C)OCC(C)OCC(C)OCC(C)OCC(C)O
ACDLabs 10.04O(CC(O)C)C(COC(C)COC(C)COC(C)COC(C)COC(C)CO)C
CACTVS 3.341C[CH](O)COC(C)COC(C)COC(C)COC(C)COC(C)COC(C)CO
FormulaC21 H44 O8
Name(20S)-2,5,8,11,14,17-HEXAMETHYL-3,6,9,12,15,18-HEXAOXAHENICOSANE-1,20-DIOL;
POLYPROPYLENE GLYCOL;
HEPTAPROPYLENE GLYCOL
ChEMBL
DrugBank
ZINC
PDB chain8bsg Chain A Residue 609 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8bsg Structural Investigation of Diclofenac Binding to Ovine, Caprine, and Leporine Serum Albumins.
Resolution1.89 Å
Binding residue
(original residue number in PDB)		D324 L327 G328 G350
Binding residue
(residue number reindexed from 1)		D324 L327 G328 G350
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005504 fatty acid binding
GO:0008289 lipid binding
GO:0015643 toxic substance binding
GO:0019825 oxygen binding
GO:0030170 pyridoxal phosphate binding
GO:0046872 metal ion binding
GO:1903981 enterobactin binding
Biological Process
GO:0009267 cellular response to starvation
GO:0051902 negative regulation of mitochondrial depolarization
GO:0072732 cellular response to calcium ion starvation
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0032991 protein-containing complex
GO:0072562 blood microparticle

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8bsg, PDBe:8bsg, PDBj:8bsg
PDBsum8bsg
PubMed36675044
UniProtP49065|ALBU_RABIT Albumin (Gene Name=ALB)

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