Structure of PDB 8b2q Chain A Binding Site BS03

Receptor Information
>8b2q Chain A (length=166) Species: 28112 (Tannerella forsythia) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
YVLQGSKWNKTTLKYYIYNSSSHLTTTERENAIRSAFALWSDKSTLSFIQ
VYNPNQADIKIKWEKGNHGDGYPFDGNTGILAHAFYPPPAGGNYAGHLHF
DGDENWSINGSGIDLITVAAHEIGHLLGIEHSNVSSALMYPYYTGIKRQL
DNDDCLAVWDLYGYPF
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain8b2q Chain A Residue 303 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8b2q A unique network of attack, defence and competence on the outer membrane of the periodontitis pathogen Tannerella forsythia.
Resolution1.35 Å
Binding residue
(original residue number in PDB)		D109 G110 T112 I114 D135 E138
Binding residue
(residue number reindexed from 1)		D75 G76 T78 I80 D101 E104
Annotation score4
Enzymatic activity
Enzyme Commision number 3.4.24.-
Gene Ontology
Molecular Function
GO:0004222 metalloendopeptidase activity
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0031012 extracellular matrix

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8b2q, PDBe:8b2q, PDBj:8b2q
PDBsum8b2q
PubMed36755705
UniProtD0EM77|KLY_TANFA Karilysin (Gene Name=kly)

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