Structure of PDB 8a7b Chain A Binding Site BS03

Receptor Information
>8a7b Chain A (length=336) Species: 80249 (Phaedon cochleariae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SKEESREFMAIFPDIVRDLTDHTDIPEVTKRFAKVLQYNVPTGKKTRGLS
TVIAYKMLEKPENLTPENVRLAGILGWCVELLQASLLIMDDLMDRSETRR
GQPCWYRQENVGFLAINDCLHVESSLYSVLRKYFSHLPCYVPIIELFHDV
NFKTNMGQSLDALCMKDGRPILSQFTMKRYSSIVKYKTSYYTFQLPVSLG
MYLADMYDPEQHRQAKTILMEIGEFFQIQNDFLDAFGDSTGKVGTDIKEG
KCSWLAVVALQRSNPAQRQIMEEHYGRPEPESTQIIKNLYIELGLPATFA
VYEEESFNIIRTHIHQISKGLPHDLFFKIMKKIYKR
Ligand information
Ligand IDCO3
InChIInChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
InChIKeyBVKZGUZCCUSVTD-UHFFFAOYSA-L
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(=O)([O-])[O-]
ACDLabs 10.04
CACTVS 3.341		[O-]C([O-])=O
FormulaC O3
NameCARBONATE ION
ChEMBL
DrugBankDB14531
ZINC
PDB chain8a7b Chain A Residue 507 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8a7b Metal-dependent enzyme symmetry guides the biosynthetic flux of terpene precursors.
Resolution1.65 Å
Binding residue
(original residue number in PDB)		R188 R189 K333
Binding residue
(residue number reindexed from 1)		R99 R100 K242
Annotation score1
Enzymatic activity
Enzyme Commision number 2.5.1.1: dimethylallyltranstransferase.
Gene Ontology
Molecular Function
GO:0004659 prenyltransferase activity
GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups
Biological Process
GO:0008299 isoprenoid biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:8a7b, PDBe:8a7b, PDBj:8a7b
PDBsum8a7b
PubMed37308711
UniProtM1JS91

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