Structure of PDB 8a3w Chain A Binding Site BS03

Receptor Information
>8a3w Chain A (length=254) Species: 347515 (Leishmania major strain Friedlin) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GKTVLSCRKGNGSVYQVHGHKRLGPAKLRILDYAERHGYMRGVVKSIEHE
AGRGAALARVEFRHPYKFRRVKELMVAPEGMFTGQSVFCGQKAPLAIGNV
LPLGQITEGCIVCNVEAKPGDRGTLARASGDYCIIISHNHETGRTRLKLP
SGQKKSVPSTSRAMIGIISGGGRIEKPVLKAGNSFYRFRGKRNCWPKVRG
VARNPVEHPHGGGNHQHIGHPSTVSRHSPPGQKVGLIAARRTGRIRGGKA
VKGA
Ligand information
>8a3w Chain 3 (length=153) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gugguaaugcggccagguaacaaaucaauccucccacggugagcuuucuu
uucaccauaauccaccuugggccuuuuuaccgcguuguucggagcggggg
cucaagauugaaaaaugcauugugaguucugcgcuaaagcaaaaaccugg
ggu
<<<....>>>..<<<<<<.......<<...<<<.<<.<<<<<<.......
>>>>>><...<<.<.<<<<<<<<<<<....<<.......>>....>>>>>
>>>>>>.>.>>....>....>>.>>>...>>.............>>>>>>
...
Receptor-Ligand Complex Structure
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PDB8a3w CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : WILD TYPE
Resolution2.89 Å
Binding residue
(original residue number in PDB)		H50 F69 R71 K177 Y187 R188
Binding residue
(residue number reindexed from 1)		H49 F68 R70 K176 Y186 R187
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005730 nucleolus
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:0022626 cytosolic ribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8a3w, PDBe:8a3w, PDBj:8a3w
PDBsum8a3w
PubMed
UniProtQ4FWX5

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