Structure of PDB 7zx4 Chain A Binding Site BS03

Receptor Information
>7zx4 Chain A (length=360) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LPIRFQEHLQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQVVIID
MNDPSNPIRRPISADSAIMNPASKVIALKAGKTLQIFNIEMKSKMKAHTM
TDDVTFWKWISLNTVALVTDNAVYHWSMEGESQPVKMFDRHSSLAGCQII
NYRTDAKQKWLLLTGISAQQNRVVGAMQLYSVDRKVSQPIEGHAASFAQF
KMEGNAEESTLFCFAVRGQAGGKLHIIEVGTPPTGNQPFPKKAVDVFFPP
EAQNDFPVAMQISEKHDVVFLITKYGYIHLYDLETGTCIYMNRISGETIF
VTAPHEATAGIIGVNRKGQVLSVCVEEENIIPYITNVLQNPDLALRMAVR
NNLAGAEELF
Ligand information
Receptor-Ligand Complex Structure
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PDB7zx4 Large-scale phosphomimetic screening identifies phospho-modulated motif-based protein interactions.
Resolution2.08 Å
Binding residue
(original residue number in PDB)		R188 Q192 I194 F216 K227 I231
Binding residue
(residue number reindexed from 1)		R184 Q188 I190 F212 K223 I227
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity
Biological Process
GO:0006886 intracellular protein transport
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0030130 clathrin coat of trans-Golgi network vesicle
GO:0030132 clathrin coat of coated pit

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7zx4, PDBe:7zx4, PDBj:7zx4
PDBsum7zx4
PubMed37219487
UniProtQ00610|CLH1_HUMAN Clathrin heavy chain 1 (Gene Name=CLTC)

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