Structure of PDB 7zle Chain A Binding Site BS03

Receptor Information
>7zle Chain A (length=284) Species: 209285 (Thermochaetoides thermophila) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SVSKTEHAEINIFSVASGHLYERMLNIMMASVMHHTNHTVKFWFIEQFLS
PSFKDFIPHMAAEYGFKYEMVTYKWPHWLRQQKEKQREIWGYKILFLDVL
FPLSLDKVIFVDADQIVRTDMYDLVEHPLDGAPYGFAPMCDSRVEMEGYR
FWKTGYWANYLKGKPYHISALYVVDLQRFRELAAGDRLRQQYHALSADPN
SLANLDQDLPNHMQFTIPIATLPQEWLWCETWCSDETLKDARTIDLCNNP
MTKEPKLDRARRQVPEWTKYDEEIAELARRVREG
Ligand information
Ligand IDPDO
InChIInChI=1S/C3H8O2/c4-2-1-3-5/h4-5H,1-3H2
InChIKeyYPFDHNVEDLHUCE-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.0C(CO)CO
ACDLabs 11.02
CACTVS 3.352		OCCCO
FormulaC3 H8 O2
Name1,3-PROPANDIOL
ChEMBLCHEMBL379652
DrugBankDB02774
ZINCZINC000001529437
PDB chain7zle Chain A Residue 1504 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7zle A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein quality control checkpoint
Resolution1.823 Å
Binding residue
(original residue number in PDB)		W1280 D1396
Binding residue
(residue number reindexed from 1)		W90 D206
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity
Biological Process
GO:0006486 protein glycosylation

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Molecular Function
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Biological Process
External links
PDB RCSB:7zle, PDBe:7zle, PDBj:7zle
PDBsum7zle
PubMed
UniProtG0SB58

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