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Receptor Information

>7yg6 Chain A (length=727) Species: 31330 (Ephydatia fluviatilis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

QRGSSGQPVPVSANYLPLKGNMDGVFKYAVGFNPPVEDIRSRSQLLNEHK
ELIGLTRVFDGSTLYVPKRICEQRLDLMSTRQTDGASIKVTISLVDSVKN
RDVVQLMNVIFKRILRSLKLQRIGRDYYDANSPLEVPQHKMQLWPGYVTA
INRHEGGLMLVLDVSHRVMKTDTALDFLYELYAFKQLVGSVVLTRYNNRT
YEIDDIAWDKNPRCAFQDHAGSQITFVDYYKRAYDLDITDLEQPLLIHRP
MVCLVPELCAMTGLTDAARSDFKVMKDLAVHTRVPPEKRAESFRKFIQRL
NTTKEASELLHSWGLVLDSRMLDMQGRRLPPEKILFKHSSIVANMEADWS
RECLKEHVISAVSLLDWAVLFVRKDQGKATDFVNMLSKVCPPIGMEVHEP
KMVEVVNDRTESYLRALRELIAPRLQMVVIVFPTSRDDRYSAVKKLCCIE
SPIPSQVLIARTITQQQKLRSVAQKVALQMNAKLGGELWAVEIPLKSCMV
VGIDVYHDKSYGNKSIAGFVASTNPSFTRWYSRTAMQELIHELKLCMQAA
LKKYNEMNQSLPERIIVFRDGVGEGREEYVSEFEVPQFNSCFSIFGENYC
PKLAVVVVQKRITTRIFGRSGHSYDNPPPGVIVDHTITKSYDFYLVSQHV
RQGTVSPTYYRVIYDKSGLKPDHLQRLTYKLTHMYYNWPGTIRTPAPCKY
AHKLAFLVGKSLHRDPAHELSDRLFFL

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

7yg6 Chain A Residue 1002 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7yg6 Structure basis of mammalian Piwi-piRNA silencing machinery
Resolution	3.2 Å
Binding residue (original residue number in PDB)	D830 K870
Binding residue (residue number reindexed from 1)	D570 K610
Annotation score	4

Enzyme Commision number

	Molecular Function
GO:0003676	nucleic acid binding
GO:0003723	RNA binding

PDB	RCSB:7yg6, PDBe:7yg6, PDBj:7yg6
PDBsum	7yg6
PubMed	38658622
UniProt	D5MRY8

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Structure of PDB 7yg6 Chain A Binding Site BS03