Structure of PDB 7y85 Chain A Binding Site BS03

Receptor Information
>7y85 Chain A (length=1232) Species: 237368 (Candidatus Scalindua brodae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNITVELTFFEPYRLVEWFDWDARKKSHSAMRGQAFAQWTWKGKGRTAGK
SFITGTLVRSAVIKAVEELLSLNNGKWEGVPCCNGSFQTDESKGKKPSFL
RKRHTLQWQANNKNICDKEEACPFCILLGRFDNAGKVHERNKDYDIHFSN
FDLDHDLRLVDIASGRILNRVDFDTGKAKDYFRTWEADYETYGTYTGRIT
LRNEHAKKLLLASLGFVDKLCGALCRIEVIDHNDELRKQAEVIVEAFKQN
DKLEKIRILADAIRTLRLHGEGVIEKDELPDGKEERDKGHHLWDIKVQGT
ALRTKLKELWQSNKDIGWRKFTEMLGSNLYLIYKKETGGFRILGDTEYYS
SDLFIPVTPPEGIETKEWIIVGRLKAATPFYFGVQQPSDSIPGKENEHTS
FNILLDKENRYRIPRSALRGALRRDLRTAFGSGCNVSLGGQILCNCKVCI
EMRRITLKDSVSDFSEPPEIRYRIAKNPGTATVEDGSLFDIEVGPEGLTF
PFVLRYRGHKFPEQLSSVIRYWEENDGKNGMAWLGGLDSTGKGRFALKDI
KIFEWDLNQKINEYIKERGMRGKEKELLEMGESSLPDGLIPYKFFEEREC
LFPYKENLKPQWSEVQYTIEVGSPLLTADTISALTEPGNRDAIAYKKRVY
NDGNNAIEPEPRFAVKSETHRGIFRTAVGRRTGDLGKEDHEDCTCDMCII
FGNEHESSKIRFEDLELINGNEFEKLEKHIDHVAIDRFTGGALDKAKFDT
YPLAGSPKKPLKLKGRFWIKKGFSGDHKLLITTALSDIRDGLYPLGSKGG
VGYGWVAGISIDDNVINNDYVHPGHQSPKQDHKNKNIYYPHYFLDSGSKV
YREKDIITHEEFTEELLSGKINCKLETLTPLIIPDTSDENGLKLQGNKPG
HKNYKFFNINGELMIPGSELRGMLRTHFEALTKSCFAIFGEDSTLSASKT
LGGKLDKALHPCTGLSDGLCPGCHLFGTTDYKGRVKFGFAKYENGPEWLI
TRGNNPERSLTLGVLESPRPAFSIPDDESEIPGRKFYLHHNGWRIIRQKQ
LEIRETVQPERNVTTEVMDKGNVFSFDVRFENLREWELGLLLQSLDPGKN
IAHKLGKGKPYGFGSVKIKIDSLHTFKIKRVPQSDIREYINKGYQKLIEW
SGLPQWHVIPHIDKLYKLLWVPFLNDSKLEPDVRYPVLNEESKGYIEGSD
YTYKKLGDKDNLPYKTRVKGLTTPWSPWNPFQ
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7y85 Chain A Residue 1801 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7y85 Structural basis for the non-self RNA-activated protease activity of the type III-E CRISPR nuclease-protease Craspase
Resolution2.73 Å
Binding residue
(original residue number in PDB)		H747 C750 C752 C755
Binding residue
(residue number reindexed from 1)		H690 C693 C695 C698
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:7y85, PDBe:7y85, PDBj:7y85
PDBsum7y85
PubMed36477448
UniProtA0A0B0EGF3

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